Vioxx Side Effects : Are You Suffering?
Have you ever taken the drug Vioxx or celebrex? In September 2004 the drug manufacturer Merck decided to recall the product after long term data suggested a serious potential side effect.
This drug and others like it such as as 'Celebrex', 'Bextra' and 'Arcoxia' are part of a family of drugs known as "COX2 drugs" or "COX2 inhibitors"
They have been developed with, ironically, patient safety in mind.They are typically used in treatment of arthritis, though high dose vioxx was promoted for short term relief of acute muscular/skeletal pains.They were anti-inflammatory drugs.
The serious side effects were in connection with the heart suggesting risk of heart disease or heart attack.In medical circles it was referred to as "..adverse cardiovascular effects."
There are other drugs used to treat inflammation that have been around for many years.YOu may have heard of products such as Advil or Nurofen which contain the ingredient Ibuprofen.Other older anti-inflammatory drugs include such brands as Voltarol or Naprosyn.
What's the difference between these older drugs and the recent treatments know as "COX2 drugs"?
The newer drugs such as Arcoxia,Celebrex and Vioxx were designed to be much more specific in their mode action than old drugs like Ibuprofen.The idea was to limit the associated problems in long term treatment.
When we get older we all seem to get more sensitive to side effects of drugs.Often this is complicated even more by the fact that we may suffer from more than one problem or disease at the same time.
At this point we take more medication in the last five to ten years of our lives than in all the other years put together! Is it any wonder we might feel under the weather, a little off colour even?
You could have asthma and high blood pressure. Anxiety and lack of sleep every night. Panic attacks and depression.
If you take an anti-inflammatory drug for a given length of time, your doctor/physician will no doubt tell you about one major problem.
Ulceration of the stomach or intestines.....
It was hoped that the newer COX2 drugs would not cause this problem at all.Therefore it would avoid the risk of someone suffering internal bleeding which could become fatal.
The older you become the greater the risk of this occuring. It could be a slow blood loss or a sudden episode of an ulcer bleeding more profusely.
So when people got the signs of ulcers, they got treatment for an ulcer. Some would stop taking medication and others would take a maintenance dose to prevent ulcers coming back while continuing to take the old ibuprofen drugs for their arthritis.
It was hoped drugs like vioxx would stop this, but ulceration still remains a possibility. Doctors routinely consider offering anti ulcer drugs to reduce the probability of this happening.
So what is the all the recent fuss about ? Where did it all suddenly seem to unravel after all that hope and expectation ? A new long term study seemed to indicate some degree of risk to the heart some 18 months or so after starting treatment.
So if you took vioxx for a week or a couple of months, this potential problem did not appear.It has only been spotted after taking the medication for a longer period such as 18 months.
What can you do? Are there ways to reduce risks? This is something you need advice on as only your doctor will have your medical history.There is much to consider and such a problem can in some circumstances be minimised.
Of course if you smoke you increase the risk of stomach or intestinal ulceration if you also take anti-inflammatory drugs such as Ibuprofen.Why not quit instead?
If you take other medication for depression or anxiety then these drugs can increase the risk of bleeding with any anti-inflammatory drug being taken at the same time.
For more related information visit
http://www.AnxietyAttacksCure.com - a site that offers advice for avoiding, coping with anxiety and panic attacks. Get professional knowledge on dealing with symptoms, drug side effects and improving your life!
You Are Getting Very Sleepy....The Truth about Hypnosis
A hypnotic "trance" is not something that is foreign to us--we've all been so absorbed in thought while reading a book or watching a movie that we fail to notice what is happening around us. These focused states of attention are similar to hypnosis. Simply put, when our minds are concentrated and focused, we are able to use them more powerfully. In this condition, we can tap into normally unused mental powers to create new possibilities of experience.
Root Canal Therapy: Frequently Asked Questions
Spin Control: What to Do When Youre Dizzy
Dizzy Dean, the great baseball pitcher of the 1930s-1940s, once quipped, "The doctors x-rayed my head and found nothing."
Ultram Story: Keeping Pain Control Under Control
When Aspirin Isn't Enough
Signs of an Addiction
Addictions come in many forms. It's important to recognize the signs of addictions in order to seek out help before the problem becomes to large.
SUPERLASIK- Enhance Your Vision; Safer Than LASIK
Things are moving forward and new and advanced procedures are being developed for those who originally could not receive the standard Lasik procedure. Dr. Khanna has introduced a brand new procedure called "Super Lasik" a new, safer and more stable procedure that has now been created for those who have thin or abnormal corneas. What is great about this new procedure is the effects are more precise and long term. This procedure is a culmination of the merger of benefits of both PRK and LASIK. To accomplish this cutting edge surgery, Dr Khanna uses a new FDA approved instrument called a Epikeratome. This instrument raises an approximately 50 micron flap (thinner than even an Intralase). Laser surface ablation using the latest generation of LASERS is than done. Like in LASIK the flap is riposted back. A bandage lens is than placed over the eye. This is a safer method of visual correction. There is no distortion of the architecture of the cornea. So if the cornea has a young's modulus which is low, or is thin or asymmetric this method is safer. Young's modulus= stress/strain
What is R.I.C.E. and why do you need it? One of the most recommended icing techniques for reducing inflammation and treating minor injuries is R.I.C.E., an acronym for rest, ice, compression and elevation. It is best used for pulled muscles, sprained ligaments, soft tissue injury, and joint aches. Applying R.I.C.E. treatments will decrease pain, inflammation, muscle spasms, swelling and tissue damage. It achieves this by reducing blood flow from local vessels near the injury and decreasing fluid hemorrhaging as a result of cell damage.
What You Should Know About Mixing Medications and Diet...
I had a call the other day from a potential client in a serious situation. He was young and had been diagnosed with CAD (Coronary Artery Disease), suffering from extremely high blood pressure and cholesterol, his doctor had put him on a medication that was suppose to lower and control these symptoms, and he had been on this medication for over 2 years.
The Neurological Exam: Evaluating the Master Organ
How does a mind contemplate itself? That's a philosophical question I'll leave to minds smarter than mine, but what I can tell you is how to examine the brain and other parts of the nervous system.
ADHD - Are there Treatment Options?
As an ADD coach I am often asked about the treatment options available for Attention Deficit Disorder. Generally when someone says "ADD" the first thing that will come to the layperson's mind is 'Ritalin' or an image of a hyperactive "Dennis-the-Menace" type. Fortunately, there is a lot more to Attention Deficit Disorder than drugs and hyperactivity. Each individual is unique and therefore different people will respond well to different treatment options.
Lunesta is a newly released sleeping pill. Marketed as a revolutionary sleep aid, Lunesta is the only medication approved by the FDA for long term treatment of insomnia symptoms. Although Lunesta is a quality medicine that has already helped many people cure their insomnia symptoms and get a better night's sleep, there is something you should know before your buy Lunesta.
Can You Always Trust Your Dentists Recommendations?
Can you always trust your dentists' recommendations? Think for yourself - in the last 30 years the health of our teeth has improved dramatically. We drink fluoridated water, which almost eliminated decay in our teeth.
CRP And Your Heart
Monitoring your CRP level is vitally important because it is one of the best indicators of heart disease. C-Reactive Protein has proven to be one of the best indicators of looming Heart disease.
Stem Cell Research
How To Buy Your Way Out Of An Early Death From An Incurable Disease.
Testosterone Therapy in XXI Century
Nowadays many people are familiar with the appellation of "low testosterone level". What does it mean? It mean that male body produce less amounts of this hormone than necessary.
Heel Pain - Ten Tips for Treatment
The most common cause of heel pain is plantar fasciitis (plan * tar fash* ee * I * tis). If you experience a sharp pain in your heel when you first step down in the morning, it is most likely due to plantar fasciitis. This type of heel pain may also occur as achiness at the end of the day in the heel or even burning pain in the arch. Plantar fasciitis can be associated with a heel spur, but this is not the cause of the pain. When the long ligament like structure (plantar fascia) on the bottom of the foot pulls on the heel bone over a period of time, a spur is formed. Only 50% of individuals with plantar fasciitis have a bone spur in their heel. The spur will never go away, but the plantar fasciitis will. Plantar fasciitis is typically caused by a new activity, a new pair of shoes, a worn out pair of shoes, a change of routine or change in job. Individuals with flatfeet or abnormal motion in the feet may have a higher chance of developing plantar fasciitis. Once you develop plantar fasciitis, you may find it very difficult to treat.
Onychomycosis - One Of The Many Nail Fungus Out There
Many natural changes in fingers and toenails come with age. Fine ridges, for example, may start developing from the cuticle of the nail tip. This and other similar changes are common, but they are not signs of poor health.
rX My Heart and Hope to Die
This must be a mistake! How could his drug costs rise from $150 a month to $1101 in just three weeks? My hands shook while I read the pharmacy bill.
How Distressing is Social Phobia?
I remember a friend in college who would blush, sweat, and tremble when required by a teacher to speak in class. A few weeks before the presentation, he'd be anxious, agitated, and couldn't sleep. Because I was still a student then, I didn't have any clue what he was going through. But I knew that something was terribly wrong.
Zoloft Side Effects: Akathisia and Violent Behavior
Zoloft is an SSRI (selective serotonin reuptake inhibitor); a prescription drug that combats depression, anxiety, posttraumatic stress disorder (PTSD), panic disorder, obsessive-compulsive disorder (OCD), as well as other various problems. SSRIs work by allowing more serotonin to be released through the brain. Seratonin is a brain chemical associated with happiness. Between nerve endings in the brain, there are synapses. All signals in the brain are transmitted through chemicals being produced then absorbed by one nerve and another. When these chemicals are released they are either taken in by the next nerve or the nerve that released them will re-absorb them and the signal doesn't pass. Some antidepressants work by blocking the reuptake of Seratonin by the releasing nerve. That means that more Seratonin stays in the synapse in the hope that it will be absorbed by the new nerve which, in the case of Seratonin, would continue the signal of happiness.
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