What is Bextra? (FDA Recalled Drug)
Bextra, also known as valdecoxib, is a prescribed medication used to alleviate the problems associated with arthritis and other inflammation-related conditions. The drug helps reduce the pain of swelling and fever without causing stomach irritation like aspirin.
NSAIDs work by blocking a chemical in the body called cycloxgenase. Cylooxgenase-1, or COX-1, shields the stomach from the harsh hydrochloric acid it contains, while COX-2, is found in inflamed tissues and causes the pain of fever, infection and arthritis. The drugs were effective for alleviating this pain, but the relief benefits were limited because the traditional NSAIDs caused stomach irritation. Taking an NSAIDs like aspirin causes pain because it blocks both chemicals (relieving pain) but also disabling the stomach protection of COX-1.
When the development of aspirin and ibuprofen came along, medical science searched for a way to provide a safe, non-addictive pain and fever relief without the risk of serious gastrointestinal damage. This came in the late 1990's when scientists isolated the protein COX-2 from COX-1 and created drugs to selectively block COX-2 without interfering with COX-1.
When these COX-2 inhibitors like Bextra were introduced, they relieved the pain of inflammation like arthritis without causing significant stomach damage. They soon became biggest selling pain relievers in the world, with sales in the tens of billions of dollars. Unfortunately, clinical trials began to warn patients about potential risks of increased cardiovascular trauma due to the disruption by COX-2 drugs of the way that the kidneys regulate blood pressure after filtering out impurities. These drugs started causing blood clots to form in the arteries causing heart attacks and strokes. Despite the documented accounts of these risks, doctors continued to prescribe Bextra in larger quantities.
Bextra is dangerous because it increases the patient's chance for heart attacks and strokes as well as endangering patients undergoing post-operative recovery for heart surgery. Patients taking Bextra also face an increased risk of developing potentially fatal skin allergies called Steven-Johnson syndrome and Toxic Epidermal Necrolysis Syndrome. After further review, the FDA re-evaluated the drug and asked Pfizer to remove the drug from the market on April 7th, 2005.
Unfortunately the damage has already been done. Bextra caused millions of people to live in fear, anxiety and illness because the were prescribed an unsafe drug. If you've suffered from these dangerous and potentially fatal side effects, you have the right to seek compensation for your physical and emotional anguish. Immediately consult your physician to assess any damage to your health and immediately contact an experienced lawyer to help you get the answers and compensation you deserve. You are entitled to help. Contact a Bextra lawyer today!
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Marketing Authorisation - Medicinal Products
Marketing Authorisation: Medicinal Products The case of R (on the application of Merck Sharp and Dohme Ltd) v Licensing Authority , concerned the application for marketing authorisation for a generic product which was based on Product C (see below).
Bextra, Vioxx and Side Effects ? Do You Need Aa Lawyer?
The recent withdrawals of the prescription medications Vioxx and Bextra from the marketplace have many people concerned. Studies show that the use of Vioxx could increase the likelihood of strokes and heart attacks; Bextra carries those same risks and also increases the chances of contracting Stevens-Johnson Syndrome, a potentially fatal skin disease. Frequently prescribed to minimize the inflammation and pain of arthritis, these prescription drugs belong to a family of non-steroidal anti-inflammatory drugs known as COX-2 inhibitors.
Tempest in a Tea Cup, Wisdom in a Sake Cup
What an oxymoron the Physicians Committee for Responsible Medicine has turned out to be. This vegan organization has one colossal ax to grind with their archrival, Darth Atkins. This is an old score that they've unfairly flung in front of the public before, all in the effort to squash the low carb idea and its adherents.
Finally...Affordable Prescription Medication without Insurance.
If you are like many Americans, you are without health insurance. And the ranks of the uninsured are growing. According to the National Coalition on Health Care (NCHC), the number of uninsured was a record breaking 45 million in 2003. The growing number of uninsured is in large part being driven by individuals abandoning the corporate life to pursue their dreams as entrepreneurs and small business owners.
What is Going On With Pharmacies in Canada
There is a large amount of talk lately in regard to Canadian pharmacies, and why not? pharmacies in Canada provide the same identical perscription drugs you would find at the local pharmacy, deliver to your front door, and most importantly, save you some cash. But not all pharmacies are the same. This article has been composed to help you to identify what you ought to look around for when doing business with Canadian pharmacies online.
SUPERLASIK- Enhance Your Vision; Safer Than LASIK
Things are moving forward and new and advanced procedures are being developed for those who originally could not receive the standard Lasik procedure. Dr. Khanna has introduced a brand new procedure called "Super Lasik" a new, safer and more stable procedure that has now been created for those who have thin or abnormal corneas. What is great about this new procedure is the effects are more precise and long term. This procedure is a culmination of the merger of benefits of both PRK and LASIK. To accomplish this cutting edge surgery, Dr Khanna uses a new FDA approved instrument called a Epikeratome. This instrument raises an approximately 50 micron flap (thinner than even an Intralase). Laser surface ablation using the latest generation of LASERS is than done. Like in LASIK the flap is riposted back. A bandage lens is than placed over the eye. This is a safer method of visual correction. There is no distortion of the architecture of the cornea. So if the cornea has a young's modulus which is low, or is thin or asymmetric this method is safer. Young's modulus= stress/strain
Health Needs of Survivors of Domestic Violence
Domestic violence is not over when the victim is safe and out of harm's way. It's not over until justice has been served. Even then, it's not over. It's not over until the victim is safe, justice has been served, and the victim is well.
The Neurological Exam: Evaluating the Master Organ
How does a mind contemplate itself? That's a philosophical question I'll leave to minds smarter than mine, but what I can tell you is how to examine the brain and other parts of the nervous system.
Celebrex? Vioxx? Can My Doctor Provide Me With Safe Prescription Painkillers?
The news has been full of the recent FDA findings on a new set of drugs to help relieve pain. These drugs have been approved for re-release, but it is unclear whether Vioxx will be available again and whether physicians will feel comfortable prescribing Celebrex and Bextra for many of their patients.
Joint Pain Relief
If you joints are constantly killing you, here are three suggestions:
Arizona Drug Rehab: Finding Help in Arizona
The state of Arizona has one of the worst drug problems in the United States. Historically and currently, the state is known as a transhipment location for a variety of drugs, including heroin, cocaine and marijuana, which are imported from other countries. As a result, these and other drugs are widely available in the state, and their abuse is common. There are probably few states that require the presence of rehabilitation centers as this one does - thankfully Arizona drug rehab centers are some of the best in the world.
Phentermine Diet Pills: When Diet and Exercise Arent Enough To Help You Lose Weight
Have you been struggling to lose weight, but diet and exercise aren't giving you the results you need to be healthy? Are you sick of people telling you that you could lose weight if only you had the will-power? It may be time to ask a physician about a phentermine prescription.
Antibiotics and Bowel Flora
The word Antibiotic is constructed from Greek words anti, which means "against" and bios, meaning "life", is a phrase used to describe an antibacterial substance made from micro-organisms, all though nowadays most are made synthetically. Antibiotics inhibit the growth or destroy other micro-organisms; penicillin, cephalosporin, amino-glycosides, streptomycin and tetracycline are all examples of common antibiotics. Penicillin is the largest group of antibiotics to be used in modern clinical medicine. Misuse and overuse of antibiotics has caused a lot of bacteria to become immune to them. This is why nowadays many hospitals are having problems in combating strains of bacteria such as methicillin-resistant staphylococcus aureus, other wise known as MRSA.
Chronic Head, Facial, Or Neck Pain That Won?t Go Away - Could It Be TMJ?
I stumbled across TMJ when I needed treat a literal pain in the neck that would not go away. It seemed that the pain in my neck came from my jaws. "TMJ" refers to disorders of the jaw muscles and of the temporomandibular joint, the hinge at the side of the head that joins the lower jaw, mandible, to the temporal bone of the skull. TMJ expert John Taddey, D.D.S. states that one the most common symptoms of TMJ is a dull, aching pain around the ears which can radiate to the neck, shoulders, and back of the head. These symptoms may be coupled with tenderness of the jaw muscles and a headache.
Treatment for High Blood Pressure
The treatment of high blood pressure is one of the most important areas of modern medicine. Good quality care and blood pressure treatment can reduce the risk of death, the risk of stroke and the risk of heart attack or coronary disease. The British Hypertension Society produced guidelines in 2004. This is what they recommend.
Using Blood Pressure Monitors To Maintain Your Health
Many people today realize the importance of keeping their blood pressure under control. Blood pressure monitors are now available for home use.
Physicians, Chiropractors and Physical Therapist Agree on a New Treatment for Low Back Pain
One of the most prevalent and difficult health conditions to treat in the physical medicine is low back pain. The difficulty in treating low back pain comes from the fact that there are numerous causes including herniated discs, bulging discs, degenerative discs, muscle spasms, facet arthritis, and sciatica. While the vast majority of low back problems are relieved in a few days, there are still millions of Americans suffering with severe and chronic pain. The number of opinions on how to treat low back pain are as numerous as the physicians trying to help the patients, until recently. The last few years has brought about a revolution in the treatment of low back pain where all types of healthcare providers agree on the best treatment.
A Closer Look at Neck Pain Relief
Neck pain afflicts many people at some point in their life - two-thirds of American adults report having experienced at least one incidence of neck pain in their lives. You can strain your neck during exercise, at work, or even something as simple as turning over in your sleep. It's an ailment so common that it has even earned it's own colloquialism. But while your boss, neighbor, or even children can all be a real "pain in the neck" sometimes, so can the pain in your neck!
10 Home Remedies For Arthritis Pain Relief
Your Remedy No. 1 ==============
Mend Your Arthritis Pain Relief
=====KNOW YOUR ARTHRITIS=====
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